An Extensive Examination of the Warning Signs, Symptoms, Diagnosis, Available Therapies, and Prognosis for Lumpy Skin Disease.
Bharti DattenAnis Ahmad ChaudharyShalini SharmaLokender SinghKrishna Dutta RawatMohammad Saquib AshrafLina M AlnegheryMalak O AladwaniHassan Ahmed RudayniDeen DayalSanjay KumarKundan Kumar ChaubeyPublished in: Viruses (2023)
The lumpy skin disease virus (LSDV) infects cattle and buffalo and causes lumpy skin disease (LSD). It affects the lymph nodes of the sick animals, causing them to enlarge and appear as lumps (cutaneous nodules) that are 2-5 cm in diameter on their heads, necks, limbs, udders, genitalia, and perinea. A high temperature, a sharp drop in milk supply, discharge from the eyes and nose, salivation, a loss of appetite, depression, damaged hides, and emaciation are further warning signs and symptoms. As per the Food and Agriculture Organization (FAO), the incubation period, or the time between an infection and symptoms, is approximately 28 days. Infected animals can transfer the virus by direct contact with the vectors, direct virus secretion from mouth or nose, shared feeding and watering troughs, and even artificial insemination. The World Organization for Animal Health (WOAH) and the FAO both warn that the spread of illnesses could lead to serious economic losses. This illness reduces cow's milk production because oral ulcers make the animal weak and lead them to lose their appetite. There are many diagnostics available for LSDV. However, very few tests yield accurate findings. The best methods for preventing and controlling the lumpy skin condition include vaccination and movement restrictions. As a specific cure is not available, the only available treatment for this illness is supportive care for cattle. Recently, India has developed a homologous, live-attenuated vaccine, Lumpi-ProVacInd, which is specifically intended to protect animals against the LSD virus. This study's primary goal is to accumulate data on symptoms, the most accurate method of diagnosis, treatments, and controls to stop infections from spreading as well as to explore future possibilities for the management of LSDV.
Keyphrases
- disease virus
- wound healing
- soft tissue
- sleep quality
- lymph node
- high temperature
- weight loss
- public health
- palliative care
- mental health
- high resolution
- optical coherence tomography
- dna damage
- depressive symptoms
- sentinel lymph node
- health information
- dna repair
- current status
- chronic pain
- gene therapy
- neoadjuvant chemotherapy
- deep learning
- early stage
- human health
- affordable care act
- optic nerve