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Accelerated differentiation of human induced pluripotent stem cells to blood-brain barrier endothelial cells.

Emma K HollmannAmanda K BaileyArchit V PotharazuM Diana NeelyAaron B BowmanEthan S Lippmann
Published in: Fluids and barriers of the CNS (2017)
Given the accelerated differentiation, equivalent performance, and reduced cost to produce BMECs, our updated methods should make iPSC-derived in vitro BBB models more accessible for a wide variety of applications.
Keyphrases
  • induced pluripotent stem cells
  • blood brain barrier
  • endothelial cells
  • cerebral ischemia
  • high glucose
  • subarachnoid hemorrhage