Pregnancy outcome after first trimester use of angiotensin AT1 receptor blockers: an observational cohort study.
Maria HoeltzenbeinTatjana Tissen-DiabatéAnne-Katrin FietzSandra ZinkeAngela KayserReinhard MeisterCorinna Weber-SchoendorferChristof SchaeferPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2018)
Our study supports the hypothesis that ARBs are not major teratogens. Patients inadvertently exposed to ARBs during the early pregnancy may be reassured. Nevertheless, women planning pregnancy should avoid ARBs. In selected cases, ARBs might be continued under careful monitoring of menstrual cycle and discontinued as soon as pregnancy is recognized.
Keyphrases
- pregnancy outcomes
- preterm birth
- end stage renal disease
- ejection fraction
- angiotensin converting enzyme
- chronic kidney disease
- newly diagnosed
- polycystic ovary syndrome
- prognostic factors
- peritoneal dialysis
- type diabetes
- metabolic syndrome
- insulin resistance
- patient reported outcomes
- skeletal muscle
- patient reported