Revamping hemothorax management: The promise of low-dose intrapleural fibrinolytic therapy as an alternative.
Mas Fazlin Mohamad JailainiYusra HashimMohamed Faisal Abdul HamidPublished in: Respirology case reports (2024)
Surgical evacuation has long been the standard treatment for hemothorax. However, some patients are not suitable candidates for surgery. Intrapleural fibrinolytic therapy (IPFT) has recently emerged as an effective alternative for managing retained hemothorax. This case report describes two patients with retained hemothorax who were unfit for surgery and were successfully treated with IPFT at our centre. Both patients were deemed unsuitable for surgery due to comorbidities and their overall functional status. They received three cycles of IPFT, each consisting of 2.5 mg of alteplase. This treatment effectively evacuated the retained hemothorax, achieving complete radiological resolution without immediate or delayed complications up to 3 months post-discharge.
Keyphrases
- minimally invasive
- low dose
- end stage renal disease
- ejection fraction
- coronary artery bypass
- newly diagnosed
- case report
- prognostic factors
- peritoneal dialysis
- stem cells
- atrial fibrillation
- coronary artery disease
- machine learning
- acute coronary syndrome
- patient reported outcomes
- risk factors
- bone marrow
- big data
- percutaneous coronary intervention
- mesenchymal stem cells
- replacement therapy
- acute ischemic stroke
- patient reported
- smoking cessation
- combination therapy