Efficacy and safety of once-weekly insulin icodec compared to once-daily insulin g U-100 in patients with type II diabetes: a systematic review and meta-analysis.

Syed Zia SaleemAreeba FareedSyed Muhammad Muneeb AkhtarSolay FarhatAmira Mohamed TahaAymar Akilimali

Published in: Diabetology & metabolic syndrome (2024)

Switching from daily Insulin Glargine U-100 to weekly Insulin Icodec showed longer TIR (%) as well as similar blood glycemic control and safety profile. Hence, it may be a good alternate option for management of longstanding T2D.

Keyphrases

glycemic control
type diabetes
blood glucose
weight loss
insulin resistance
physical activity
metabolic syndrome
skeletal muscle
adipose tissue