The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study.

Magnus AspingNis StrideDitte SøgaardTine Lovsø DohlmannJørn W HelgeFlemming DelaSteen Larsen

Published in: European journal of clinical pharmacology (2017)

Two weeks of statin (S or P) treatment have no major effect on mitochondrial function. The tendency for an increased mitochondrial substrate sensitivity after simvastatin treatment could be an early indication of the negative effects linked to statin treatment.

Keyphrases

cardiovascular disease
oxidative stress
coronary artery disease
middle aged
type diabetes
replacement therapy
preterm birth
smoking cessation
respiratory tract