The antiproliferative and apoptotic effects of apigenin on glioblastoma cells.

Trevor A StumpBrittany N SanteeLauren P WilliamsRachel A KunzeChelsae E HeinzeEric D HusemanRebecca J GrykaDenise S SimpsonSamson Amos

Published in: The Journal of pharmacy and pharmacology (2017)

Our results demonstrated that apigenin has potent inhibitory effects on pathways involved in GBM proliferation and survival and could potentially be used as a therapeutic agent for GBM.

Keyphrases

induced apoptosis
cell death
cell cycle arrest
signaling pathway
anti inflammatory
endoplasmic reticulum stress
free survival