Association between urinary free light chains and progression to end stage renal disease in chronic kidney disease.

Anthony FentonMark D JeskyRachel WebsterStephanie J StringerPunit YadavIain ChappleIndranil DasguptaStephen J HardingCharles J FerroPaul Cockwell

Published in: PloS one (2018)

Urinary FLCs have an association with progression to ESRD in patients with CKD which appears to be explained to a degree by their correlation with eGFR and ACR. Levels above the 75th centile do have an independent association with ESRD, but do not improve upon a current model for risk stratification.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase