Detecting SARS-CoV-2 Orf3a and E ion channel activity in COVID-19 blood samples.
Han-Gang YuGina SizemoreKaty SmootPeter PerrottaPublished in: Journal of clinical and translational science (2021)
We developed a cell-free test that can detect Orf3a/E channel activity of SARS-CoV-2 in blood samples from COVID-19-infected individuals, confirming a hypothesis that the virus spreads to the heart via blood circulation.