Metformin Improves Fertility in Obese Males by Alleviating Oxidative Stress-Induced Blood-Testis Barrier Damage.

Jifeng YeDandan LuoXiaolin XuMingqi SunXiaohui SuZhenhua TianMeijie ZhangChunxiao Yu Qingbo Guan

Published in: Oxidative medicine and cellular longevity (2019)

Metformin improves obese male fertility by alleviating oxidative stress-induced BTB damage. These findings provide new insights into the effect of metformin on various diseases and suggest future possibilities in the treatment of male infertility.

Keyphrases

adipose tissue
weight loss
metabolic syndrome
oxidative stress
type diabetes
obese patients
childhood cancer
current status
skeletal muscle
young adults
insulin resistance
combination therapy
germ cell