Mediating Effect of Pain Sensitization on the Paradoxical Relation of Opioid Use to Pain Severity in Knee Osteoarthritis: The MOST Study.

Pain sensitization had small mediating effects on the paradoxical phenomenon of OIH, suggesting that pain sensitization may not play a major role and/or that PPT is an inadequate tool to assess OIH. This article is protected by copyright. All rights reserved.