Towards a clinically-based common coordinate framework for the human gut cell atlas: the gut models.

Albert Burger Richard A Baldock David J Adams Shahida Din Irene Papatheodorou Michael Glinka Bill HillDerek HoughtonMehran Sharghi Michael Wicks Mark J Arends

Published in: BMC medical informatics and decision making (2023)

Small and large intestines have a natural "gut coordinate" system best represented as a 1D centreline through the gut tube, reflecting functional differences. Such a 1D centreline model with landmarks, visualised using viewer software allows interoperable translation to both a 2D anatomogram model and multiple 3D models of the intestines. This permits users to accurately locate samples for data comparison.

Keyphrases

single cell
endothelial cells
electronic health record
mesenchymal stem cells
induced pluripotent stem cells
artificial intelligence
clinical evaluation