Identification and characterization of a novel adiponectin receptor agonist adipo anti-inflammation agonist and its anti-inflammatory effects in vitro and in vivo.

Wei Qiu Hongle Wu Zhekai Hu Xingwen Wu Maxwell Tu Fuchun Fang Zoe Xiaofang Zhu Yao Liu Junxiang Lian Paloma Valverde Thomas E Van DykeBjorn SteffensenLily Q Dong Qisheng Tu Xuedong Zhou Jake Chen

Published in: British journal of pharmacology (2020)

AdipoAI is a promising alternative therapeutic approach to APN and APR to suppress inflammation in LPS-induced endotoxemia and other inflammatory disorders via distinct signalling pathways.

Keyphrases

lps induced
oxidative stress
inflammatory response
metabolic syndrome
type diabetes