Fracture rate and time to fracture in dogs with appendicular osteosarcoma receiving finely fractionated compared to coarsely fractionated radiation therapy: A single institution study.
Carissa J NorquestCharles A MaitzDeborah A KeysMelanie MooreJeffrey N BryanTara Jean EhlingJimmy C LattimerBrian K FlesnerPublished in: Veterinary medicine and science (2022)
In conclusion, C-RT is recommended over F-RT due to lower risk of pathologic fracture and similar PFI. Prospective evaluation of combined C-RT and zoledronate, especially for dogs with poor surgical candidacy, is warranted for the treatment of canine appendicular osteosarcoma.