Unraveling the 2,3-diketo-L-gulonic acid-dependent and -independent impacts of L-ascorbic acid on somatic cell reprogramming.

Lining LiangMeiai HeYixin ZhangChenchen WangZhaohui QinQian LiTingting YangFei MengYusheng ZhouHaofei GeWeining SongShiyu ChenLinna DongQiwen RenChangpeng LiLin GuoHao SunWei ZhangDuanqing PeiHui Zheng

Published in: Cell & bioscience (2023)

These findings unveil the intricate functions of Asc in the context of reprogramming. This study sheds light on the DKG-dependent and -independent activities of Asc during reprogramming, offering novel insights that may extend the application of Asc to other biological processes.

Keyphrases

nlrp inflammasome
single cell
cell therapy
copy number
stem cells
gene expression