Predictors of survival and time to progression following operative management of intramedullary spinal cord astrocytomas.
Andrew M HershAlbert AntarZach PenningtonNafi AygunJaimin PatelEarl GoldsboroughJose L PorrasAladine A ElsamadicyAllan J BelzbergJean-Paul WolinskyGeorge I JalloZiya L GokaslanSheng-Fu Larry LoDaniel M SciubbaPublished in: Journal of neuro-oncology (2022)
Tumor grade and chemotherapy were associated with poorer survival and progression-free survival. Chemotherapy regimens were highly heterogeneous, and randomized trials are needed to determine if any optimal regimens exist. Additionally, GTR was associated with improved survival, and patients should be counseled about the benefits and risks of resection extent.