Epigenetic approach in obesity: DNA methylation in a prepubertal population which underwent a lifestyle modification.

Cristina Gallardo-EscribanoVerónica BuonaiutoM Isabel Ruiz-MorenoAntonio Vargas-CandelaAlberto Vilches-PerezJavier Benitez-PorresAngel Ramon Romance-GarciaAlejandro Ruiz-MorenoRicardo Gomez-HuelgasMaria Rosa Bernal-Lopez

Published in: Clinical epigenetics (2020)

It was found that DNAm of genes related to lipid metabolism and inflammation are also present in childhood and that this methylation profile can be modified by interventions based on MedDiet and PA.

Keyphrases

dna methylation
genome wide
metabolic syndrome
weight loss
physical activity
gene expression
insulin resistance
oxidative stress
type diabetes
copy number
cardiovascular disease
weight gain
high fat diet induced
nk cells
bioinformatics analysis
young adults
genome wide identification