GCK gene-body hypomethylation is associated with the risk of coronary heart disease.

Limin XuDawei ZhengLingyan WangDanjie JiangHaibo LiuLeiting XuQi LiaoLina ZhangPanpan LiuXinbao ShiZhaoyang WangLebo SunQingyun ZhouNi LiYi HuangYanping LeMeng YeGuofeng ShaoShiwei Duan

Published in: BioMed research international (2014)

Our study indicated that the hypomethylation of GCK gene-body was significantly associated with the risk of CHD. Aging correlates with an elevation of GCK methylation in healthy controls.

Keyphrases

genome wide
copy number
genome wide identification
dna methylation
gene expression
transcription factor