The long noncoding RNA MALAT1 suppresses miR-211 to confer protection from ultraviolet-mediated DNA damage in vitiligo epidermis by upregulating sirtuin 1.
H D BrahmbhattR GuptaA GuptaS RastogiR MisriA MobeenA GhoshP KothariS SitaniyaVinod ScariaArchana SinghPublished in: The British journal of dermatology (2020)
These findings establish a novel MALAT1-miR-211-SIRT1 signalling axis that potentially confers protection to the 'amelanotic' keratinocytes in vitiligo.