Minocycline-Loaded Poly(α-Lipoic Acid)-Methylprednisolone Prodrug Nanoparticles for the Combined Anti-Inflammatory Treatment of Spinal Cord Injury.

Feng LinYixuan LiuWenqi LuoShuhan LiuYiming WangRui GuWanguo LiuChunsheng Xiao

Published in: International journal of nanomedicine (2022)

The MC-PαLA-MP NPs can mitigate secondary inflammation and preserve motor function following experimental TSCI, which suggests their potential for clinical application.

Keyphrases

spinal cord injury
anti inflammatory
cancer therapy
oxidative stress
drug delivery
spinal cord
high dose
neuropathic pain
drug release
human health
climate change
wound healing
smoking cessation