A Rapid, Simple, Trace, Cost-Effective, and High-Throughput Stable Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry Method for Serum Methylmalonic Acid Quantification and Its Clinical Applications.
Lizi JinZhenni LiuWeiyan ZhouJie ZengMinhang WuYu ZhangTianjiao ZhangFalin HeChuanbao ZhangPublished in: Diagnostics (Basel, Switzerland) (2022)
A convenient LC-MS/MS method for serum MMA measurement was developed and validated, which could be suitable for large-scale MMA testing and evaluating MMA levels in VB12-deficient patients.