Recent urbanization in China is correlated with a Westernized microbiome encoding increased virulence and antibiotic resistance genes.
Kathryn WingleeAnnie Green HowardWei ShaRaad Z GharaibehJiawu LiuDonghui JinAnthony A FodorPenny Gordon-LarsenPublished in: Microbiome (2017)
Our data suggest that urbanization has produced convergent evolution of the gut microbial composition in American and urban Chinese populations, resulting in similar compositional patterns of abundant microbes through similar lifestyles on different continents, including a loss of potentially beneficial bacteria and an increase in potentially harmful genes via increased relative abundance of Escherichia and Shigella.
Keyphrases
- antibiotic resistance genes
- microbial community
- wastewater treatment
- anaerobic digestion
- escherichia coli
- pseudomonas aeruginosa
- staphylococcus aureus
- genome wide
- electronic health record
- biofilm formation
- antimicrobial resistance
- big data
- dna methylation
- artificial intelligence
- bioinformatics analysis
- genome wide analysis