Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury.
Sanjin HosicWill LakeEric StasRyan KoppesDavid T BreaultShashi K MurthyAbigail N KoppesPublished in: Cellular and molecular bioengineering (2020)
A primary model of intestinal inflammation was evaluated, demonstrating nAChR or mAChR activation does not have the same protective effects compared to immortalized epithelium. Inclusion of other native stromal support cells are underway.