Evaluation of extracellular matrix protein expression and apoptosis in the uterosacral ligaments of patients with or without pelvic organ prolapse.

Ya-Pei ZhuTing XieTao GuoZhi-Jing SunLan ZhuJing-He Lang

Published in: International urogynecology journal (2020)

ECM in the USL tissues of POP patients is remodeled compared with non-POP patients and is characterized by decreased synthesis and increased degradation of collagen; moreover, the levels of the main proteins involved in apoptosis are increased in POP tissue.

Keyphrases

extracellular matrix
end stage renal disease
ejection fraction
newly diagnosed
oxidative stress
peritoneal dialysis
cell death
prognostic factors
endoplasmic reticulum stress
cell proliferation