Systematic review with meta-analysis: conditioned pain modulation in patients with the irritable bowel syndrome.

Ahmed Albusoda James K RuffleKathrine A FriisMaximilian R GysanAsbjørn M DrewesQasim AzizAdam Donald Farmer

Published in: Alimentary pharmacology & therapeutics (2018)

Conditioned pain modulation is significantly diminished in patients with IBS vs healthy controls. These data suggest that abnormal descending pathways may play an important pathophysiological role in IBS, which could represent an investigation and a therapeutic target in IBS.

Keyphrases

irritable bowel syndrome
chronic pain
pain management
neuropathic pain
electronic health record
big data
machine learning
spinal cord injury
artificial intelligence
deep learning
data analysis