Hydrogel-load exosomes derived from dendritic cells improve cardiac function via Treg cells and the polarization of macrophages following myocardial infarction.
Youming ZhangZichun CaiYunli ShenQizheng LuWei GaoXin ZhongKang YaoJie YuanHaibo LiuPublished in: Journal of nanobiotechnology (2021)
Our novel delivery method provides an innovative tool for enhancing the therapeutic effects of DEXs after MI. Further analysis revealed that DEXs exert effect by activating Treg cells and by modifying the polarization of macrophages.