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Effects of Ammonium Chloride on Ozone-induced Airway Inflammation: the Role of Slc26a4 in the Lungs of Mice.

Jong Uk LeeHyeon Ju LeeJi Na KimMin Kyung KimSung Roul KimHun Soo ChangChoon-Sik ParkJong Sook Park
Published in: Journal of Korean medical science (2020)
Slc26a4 may be involved in O₃-induced inflammatory and epithelial changes in the airways via activation of the inflammasome and the induction of IL-17 and IFN-γ. NH₄Cl shows a potential as a therapeutic agent for controlling O₃-induced airway inflammation and epithelial damage by modulating Slc26a4 expression.
Keyphrases
  • high glucose
  • diabetic rats
  • drug induced
  • immune response
  • cystic fibrosis
  • signaling pathway
  • adipose tissue
  • hydrogen peroxide
  • skeletal muscle
  • air pollution
  • human health
  • metal organic framework