Effects of Ammonium Chloride on Ozone-induced Airway Inflammation: the Role of Slc26a4 in the Lungs of Mice.
Jong Uk LeeHyeon Ju LeeJi Na KimMin Kyung KimSung Roul KimHun Soo ChangJong-Sook ParkJong Sook ParkPublished in: Journal of Korean medical science (2020)
Slc26a4 may be involved in O₃-induced inflammatory and epithelial changes in the airways via activation of the inflammasome and the induction of IL-17 and IFN-γ. NH₄Cl shows a potential as a therapeutic agent for controlling O₃-induced airway inflammation and epithelial damage by modulating Slc26a4 expression.