The Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid: Systematic Review and Meta-analysis.

Mingkwan Na Takuathung Wannachai Sakuludomkan Nut Koonrungsesomboon

Published in: Clinical pharmacokinetics (2021)

The present systematic review and meta-analysis identified six SNPs that were significantly associated with pharmacokinetic variability or adverse effects of MPA. Our findings represent the basis for future research and clinical implications with regard to the role of pharmacogenetics in MPA pharmacokinetics and drug response.

Keyphrases

adverse drug
current status
genome wide
emergency department
gene expression
electronic health record