Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease.
Kazuharu IgarashiKeishi YamashitaHiroshi KatohKeita KojimaYosuke OoizumiNobuyuki NishizawaRyo NishiyamaHiroshi KawamataHiroshi TajimaTakashi KaizuYusuke KumamotoMasahiko WatanabePublished in: PloS one (2017)
Promoter NA methylation of CDO1 was demonstrated for the first time to be a cancer-associated methylation in primary GBC, and it has the potential to be a prognostic biomarker of GBC for high-risk patients with stage II GBC.