Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease.

Kazuharu IgarashiKeishi YamashitaHiroshi KatohKeita KojimaYosuke OoizumiNobuyuki NishizawaRyo NishiyamaHiroshi KawamataHiroshi TajimaTakashi KaizuYusuke KumamotoMasahiko Watanabe

Published in: PloS one (2017)

Promoter NA methylation of CDO1 was demonstrated for the first time to be a cancer-associated methylation in primary GBC, and it has the potential to be a prognostic biomarker of GBC for high-risk patients with stage II GBC.

Keyphrases

dna methylation
genome wide
gene expression
transcription factor
papillary thyroid
copy number
circulating tumor
single molecule
cell free
squamous cell
living cells
human health
fluorescent probe
climate change
circulating tumor cells