Holothuria scabra Extract Induces Cell Apoptosis and Suppresses Warburg Effect by Down-Regulating Akt/mTOR/HIF-1 Axis in MDA-MB-231 Breast Cancer Cells.

Laphatrada YurasakpongSomjai ApisawetakanKanta PranweerapaiboonPrasert SobhonKulathida Chaithirayanon

Published in: Nutrition and cancer (2020)

Overall findings indicated that H. scabra extract could be a possible therapeutic against breast cancer progression in patients with hyperglycemia, for instance, diabetes mellitus.

Keyphrases

breast cancer cells
cell proliferation
signaling pathway
oxidative stress
anti inflammatory
endothelial cells
pi k akt
metabolic syndrome
glycemic control
breast cancer risk