Dual Specific Phosphatase 14 Deletion Rescues Retinal Ganglion Cells and Optic Nerve Axons after Experimental Anterior Ischemic Optic Neuropathy.

Varun KumarMohammad Ali ShariatiLouise Mesentier-LouroAngela Jinsook OhKristina RussanoJeffrey L GoldbergYaping Joyce Liao

Published in: Current eye research (2020)

Abbreviations: AION: anterior ischemic optic neuropathy; Dusp14: dual specific phosphatase 14; ERK1/2: extracellular signal-regulated kinases 1/2; Elk-1: ETS Like-1 protein; GCC: ganglion cell complex; GCL: ganglion cell layer; inner nuclear layer; KO: knockout; MAPK: mitogen-activated phosphokinase; OCT: optical coherence tomography; RGC: retinal ganglion cell; RNFL: retinal nerve fiber layer.

Keyphrases

optic nerve
optical coherence tomography
single cell
diabetic retinopathy
cell therapy
transcription factor
protein kinase
neuropathic pain
stem cells
cell proliferation
spinal cord injury
mesenchymal stem cells
spinal cord
pi k akt
cell cycle arrest
immune response
nuclear factor
endoplasmic reticulum stress