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The multidisciplinary management of locally advanced rectal cancer.

Francesca De FeliceMichelangelo MicciniAndrea BotticelliMichela RobertoNiccolò Petrucciani
Published in: Expert review of anticancer therapy (2024)
The year 2020 has seen promising new data from randomized phase III trials in the field of LARC management. Nowadays, TNT strategy has been accepted as the primary treatment for LARC. The role of de-escalation strategies is still unknown. The goal is to achieve better survival outcomes with improving quality of life. Only selected patients are likely to benefit from NOM or immunotherapy alone.
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