Assessment of longitudinal changes in body composition of children with lymphoma and rhabdomyosarcoma.

Aman WadhwaShawn LimChen DaiGabriel DanielsKandice AdamsJoshua S RichmanAndrew McDonaldGrant R WilliamsSmita Bhatia

Published in: Cancer (2023)

We show that among children, adolescents, and young adults with lymphoma and rhabdomyosarcoma receiving chemotherapy, skeletal muscle density declines early during treatment. Additionally, a decline in skeletal muscle density is associated with a greater risk of nonhematologic chemotoxicities.

Keyphrases

skeletal muscle
body composition
young adults
diffuse large b cell lymphoma
insulin resistance
resistance training
bone mineral density
squamous cell carcinoma
adipose tissue
radiation therapy
rectal cancer