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Detection and genome characterization of two novel papillomaviruses and a novel polyomavirus in tree shrew (Tupaia belangeri chinensis) in China.

Ping LiuYe QiuCheng XingJi-Hua ZhouWei-Hong YangQiong WangJin-Yan LiXi HanYun-Zhi ZhangXing-Yi Ge
Published in: Virology journal (2019)
Two novel PVs (TbelPV1 and TbelPV2) and a novel PyV (TbelPyV) were discovered in tree shrews and their genomes were characterized. TbelPV1, TbelPV2, and TbelPyV1 have the highest similarity to Human papillomavirus type 63, Ursus maritimus papillomavirus 1, and Human polyomavirus 9, respectively. TbelPV1 and TbelPV2 only showed oral tropism, while TbelPyV1 showed oral and spleen tropism.
Keyphrases
  • endothelial cells
  • genome wide
  • loop mediated isothermal amplification
  • label free
  • dna methylation