Total Synthesis of Lissodendoric Acid A.
Francesca M IppolitiLaura G WonilowiczNathan J AdamsonEvan R DarziJoyann S DonaldsonDaniel J NasrallahMilauni M MehtaAndrew V KelleghanK N HoukNeil K GargPublished in: Angewandte Chemie (International ed. in English) (2024)
We describe a full account of our synthetic strategy leading to the first total synthesis of the manzamine alkaloid lissodendoric acid A . These efforts demonstrate that strained cyclic allenes are valuable synthetic building blocks and can be employed efficiently in total synthesis.
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