Clinical Features and Genetic Analysis of Taiwanese Primary Immunodeficiency Patients with Prolonged Diarrhea and Monogenetic Inflammatory Bowel Disease.

Wen-I LeeChien-Chang ChenShih-Hsiang ChenWan-Tz LaiTang-Her JaingLiang-Shiou OuChi-Jou LiangChen-Chen KangJing-Long Huang

Published in: Journal of clinical immunology (2023)

When compared to those with the SD phenotype, the mono-IBD patients had significant early-onset and poor responses to empiric antibiotics, IVIG, and steroids. Anti-inflammatory biologics and suitable HSCT still have the potential to control or even cure the mono-IBD phenotype.

Keyphrases

early onset
late onset
anti inflammatory
end stage renal disease
ejection fraction
ulcerative colitis
prognostic factors
irritable bowel syndrome