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NF1 alterations in cancers: therapeutic implications in precision medicine.

Jean-Stéphane GiraudIvan BiècheÉric PasmantCamille Tlemsani
Published in: Expert opinion on investigational drugs (2023)
gene. Currently, most studies are focusing on inhibitors of the RAS/MAPK and PI3K-AKT-mTOR pathways and immunotherapies.
Keyphrases
  • signaling pathway
  • pi k akt
  • oxidative stress
  • copy number
  • lps induced
  • genome wide
  • case control
  • wild type
  • genome wide identification
  • nuclear factor
  • cell proliferation
  • dna methylation
  • transcription factor