Bidirectional association between inflammatory bowel disease and depression among patients and their unaffected siblings.
Bing ZhangHo-Hui Eileen WangYa-Mei BaiShih-Jen TsaiTung-Ping SuTzeng-Ji ChenYen-Po WangMu-Hong ChenPublished in: Journal of gastroenterology and hepatology (2022)
This population-based study elucidates bidirectional association between IBD and depression. Elevated risks for either disease among patients and their unaffected siblings suggest shared etiologic contributors, offering novel insight into the gut-brain axis' influence in IBD pathophysiology.