Adenovirus vaccine targeting kinases induces potent antitumor immunity in solid tumors.

Fei ZhuZheng LuWenjing TangGuangya ZhaoYingxiang ShaoBowen LuJiage DingYanyan ZhengLin FangHuizhong LiGang WangRenjin ChenJun-Nian Zheng Dafei Chai

Published in: Journal for immunotherapy of cancer (2024)

Our findings illustrate that the Ad-AURKA/CDK7 vaccine targeting dual kinases AURKA and CDK7 emerges as a promising and effective therapeutic approach for the treatment of solid tumors.

Keyphrases

cell cycle
cancer therapy
drug delivery
cell proliferation
combination therapy
gene therapy