Epidemiology, evolutionary origin, and malaria-induced positive selection effects of G6PD-deficient alleles in Chinese populations.

Yuzhong ZhengJun-Li WangXueyan LiangHuiying HuangYanbo MaLiyun LinChunfang WangXiaofen ZhanLiye YangGuangcai ZhaPeikui YangXianghui ZouZikai ChenXinyao ChenWeizhong ChenXiangzhi LiuMin Lin

Published in: Molecular genetics & genomic medicine (2020)

These results indicate that malaria has had a major impact on the Chinese genome since the introduction of rice agriculture.

Keyphrases

plasmodium falciparum
genome wide
high glucose
climate change
diabetic rats
risk factors
drug induced
endothelial cells
oxidative stress
dna methylation