Increased elasticity of sucrose demand during hyperdopaminergic states in rats.
A Maryse MinnaardMieneke C M LuijendijkAnnemarie M BaarsLisa DrostGeert M J RamakersRoger A H AdanHeidi M B LesscherLouk J M J VanderschurenPublished in: Psychopharmacology (2022)
Stimulation of mesocorticolimbic dopaminergic neurotransmission altered cost-benefit trade-offs in a complex manner. It reduced the essential value of palatable food, increased incentive motivation and left free consumption unaltered. Together, these findings imply that mesocorticolimbic dopamine signalling differentially influences distinct components of cost expenditure processes aimed at obtaining rewards.
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