Epileptogenic focal lesions in Dravet syndrome: A warning to investigators.
Rita Monteiro VenturaÁlvaro Beltrán-CorbelliniRafael ToledanoIrene Sánchez-Miranda RománIrene García-MoralesAntonio Gil-NagelPublished in: Epileptic disorders : international epilepsy journal with videotape (2023)
When an individual with an established diagnosis of genetic epilepsy and a focal lesion on MRI is undergoing preoperative evaluation, it is crucial to conduct a comprehensive analysis to understand the relevance of the focal finding for the patient's phenotype and thus anticipate potential surgical outcomes. In instances where epilepsy in DS patients is influenced by a specific focal structural lesion, resective surgery should be carefully considered after precise pharmacological treatment, acknowledging the persistent influence of an SCN1A variant on expected outcomes.
Keyphrases
- end stage renal disease
- ejection fraction
- case report
- newly diagnosed
- chronic kidney disease
- minimally invasive
- patients undergoing
- type diabetes
- computed tomography
- gene expression
- coronary artery bypass
- patient reported outcomes
- adipose tissue
- dna methylation
- acute coronary syndrome
- skeletal muscle
- insulin resistance
- magnetic resonance
- temporal lobe epilepsy