Validated automatic speech biomarkers in primary progressive aphasia.

Naomi NevlerSharon AshDavid J IrwinMark LibermanMurray Grossman

Published in: Annals of clinical and translational neurology (2018)

Restricted fundamental frequency range and increased pause rate are characteristic markers of speech in non-fluent/agrammatic primary progressive aphasia. These can be extracted with automated speech analysis and are associated with left inferior frontal atrophy and cerebrospinal phosphorylated tau level.

Keyphrases

multiple sclerosis
deep learning
machine learning
hearing loss
high throughput
functional connectivity