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Shall we stay, or shall we switch? Continued anti-VEGF therapy versus early switch to dexamethasone implant in refractory diabetic macular edema.

Catharina BuschDinah ZurSamantha Fraser-BellInês LaínsAna Rita SantosMarco LupidiCarlo CaginiPierre-Henry GabrielleAude CouturierValérie Mané-TautyErmete GiancipoliGiuseppe D'Amico RicciZafer CebeciPatricio J Rodríguez-ValdésVoraporn ChaikitmongkolAtchara AmphornphruetIsaac HindiKushal AgrawalJay ChhablaniAnat LoewensteinMatias IglickiMatus Rehaknull null
Published in: Acta diabetologica (2018)
In a real-world setting, eyes with DME considered refractory to anti-VEGF therapy after three monthly injections which were switched to DEX implant and had better visual and anatomical outcomes at 12 months than those that continued treatment with anti-VEGF therapy.
Keyphrases
  • vascular endothelial growth factor
  • endothelial cells
  • low dose
  • metabolic syndrome
  • soft tissue
  • optical coherence tomography
  • skeletal muscle
  • adipose tissue
  • high dose
  • insulin resistance
  • bone marrow
  • ultrasound guided