Humoral and Cellular Immune Response after Three Doses of Sinopharm [Vero Cell]-Inactivated COVID-19 Vaccine in Combination with SARS-CoV-2 Infection Leads to Hybrid Immunity.
Marija VukčevićKatarina ŠerovićMateja DespotAleksandra Nikolić KokićAleksandra VujovićMilan NikolićDuško BlagojevićTanja JovanovićDragana DespotPublished in: Pharmaceuticals (Basel, Switzerland) (2024)
Our results confirm the emergence of hybrid immunity, which is the strongest and most durable compared to natural immunity or vaccine-induced immunity. Significant positive correlations were found between humoral and cellular immunity markers: neutralizing antibodies, anti-S1 IgG and anti-N IgG antibodies, and INF γ, indicating a unique coordinated response specific to COVID-19.