Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.

Jinling XuHuaxing MaLingfeng ShiHui ZhouYangyang ChengJiayue TongBiying MengXiaoli XuKaiyue HeSheng DingZhang JiajiaLing YueGuangda Xiang

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

The findings support a role for inflammatory cell-derived MYDGF served as a cross talk factor between inflammatory cells and endothelial cells that inhibits LDL transcytosis across endothelium. MYDGF may become a novel therapeutic drug for atherosclerosis, and the beneficial effects of inflammatory cell in atherosclerosis deserve further attention.

Keyphrases

endothelial cells
oxidative stress
blood brain barrier
cardiovascular disease
induced apoptosis
nitric oxide
emergency department
working memory
single cell
stem cells
cell therapy
cell proliferation
cell death
high glucose