CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype.
Han LiFan LuoXingyu JiangWeijing ZhangTong XiangQiuzhong PanLiming CaiJingjing ZhaoDesheng WengYue LiYuhu DaiFengze SunChaopin YangYue HuangJieying YangYan TangYulong HanMian HeYanna ZhangLibing SongJian-Chuan XiaPublished in: Journal for immunotherapy of cancer (2022)
This study reveals a novel mechanism for platinum resistance in OC and demonstrates that circITGB6 may serve as a potential prognostic marker and a therapeutic target for patients with OC.
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