Elevated serum TARC levels precede classic Hodgkin lymphoma diagnosis by several years.
Arjan DiepstraIlja Maria NolteAnke van den BergLarry I MagpantayOtoniel Martinez-MazaLynn I LevinPublished in: Blood (2023)
Tumor cells in classic Hodgkin lymphoma produce high quantities of the chemokine TARC. We measured TARC levels in pre-diagnostic serum samples and found strikingly increased values in the vast majority of patients, up to over six years before diagnosis.