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The safety of vedolizumab in a patient with Crohn's disease who developed anti-TNF-alpha agent associated latent tuberculosis infection reactivation: A case report.

Yuya SugiyamaNobuhiro UenoShion TachibanaYu KobayashiYuki MurakamiTakahiro SasakiAki SakataniKeitaro TakahashiKatsuyoshi AndoShin KashimaKentaro MoriichiHiroki TanabeToshikatsu OkumuraMikihiro Fujiya
Published in: Medicine (2023)
This case report presented a patient in whom VDZ was continued as maintenance therapy without inducing TB relapse in a patient with CD who developed latent TB infection reactivation associated with anti-TNF-alpha agents and summarized the safety profile of VDZ for patients with IBD with active or latent TB infection. VDZ may be a safe option for induction and maintenance therapy in patients with CD, even in cases with latent TB infection reactivation.
Keyphrases
  • case report
  • mycobacterium tuberculosis
  • rheumatoid arthritis
  • mesenchymal stem cells
  • ulcerative colitis
  • bone marrow
  • hiv aids
  • drug induced
  • free survival