The safety of vedolizumab in a patient with Crohn's disease who developed anti-TNF-alpha agent associated latent tuberculosis infection reactivation: A case report.
Yuya SugiyamaNobuhiro UenoShion TachibanaYu KobayashiYuki MurakamiTakahiro SasakiAki SakataniKeitaro TakahashiKatsuyoshi AndoShin KashimaKentaro MoriichiHiroki TanabeToshikatsu OkumuraMikihiro FujiyaPublished in: Medicine (2023)
This case report presented a patient in whom VDZ was continued as maintenance therapy without inducing TB relapse in a patient with CD who developed latent TB infection reactivation associated with anti-TNF-alpha agents and summarized the safety profile of VDZ for patients with IBD with active or latent TB infection. VDZ may be a safe option for induction and maintenance therapy in patients with CD, even in cases with latent TB infection reactivation.