Brains with sporadic Creutzfeldt-Jakob disease and copathology showed a prolonged end-stage of disease.
Aitzol Miguelez-RodriguezJorge Santos-JuanesIkerne Vicente-EtxenausiaKatty Perez de Heredia-GoñiBeatriz GarciaLuis M QuirosLaura Lorente-GeaIsabel Guerra-MerinoJose J AguirreIvan Fernandez-VegaPublished in: Journal of clinical pathology (2017)
The existence of copathology significantly prolongs survival in patients with rapidly progressive dementia due to CJD. The study of major neurodegenerative-associated proteins in brains with CJD could allow us to further understand the molecular mechanisms behind prion diseases.